1) Hypertension.

Angiopoietin-1 and Pulmonary Hypertension

Our very existence depends on the air that we breathe, as well as the remarkable systems that have evolved to ensure that the oxygen we take into our lungs is efficiently delivered to the rest of the body via the bloodstream. When these systems begin to fail, life itself can become quite tenuous. Such failure occurs in pulmonary hypertension, a rare but serious disease whose pathophysiology rem...

Everyday General Practitioner Challenges: Arterial Hypertension "Methods of Diagnosis, Identification, Cause, and Significance of Disease (1)"

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Role of Endothelin-1 in Clinical Hypertension

Hypertension is the most common risk factor worldwide for cardiovascular morbidity and mortality.1,2 Currently it is estimated that a quarter of the world’s adult population is hypertensive, and this number is projected to increase to 30% by 2025.1 Although, there exist a number of drug therapies for hypertension, blood pressure (BP) control to target is still only achieved in 30% of patients.3...

1 Harmful or Helpful Hypertension – Pathophysiological Basis

Hypertension in Chronic Kidney Disease Part 1

Hypertension is highly prevalent in chronic kidney disease (CKD), particularly in patients with end-stage renal disease (ESRD) receiving hemodialysis. The identification and treatment of hypertension in CKD has to face peculiar problems because of the marked alterations in 24-hour blood pressure (BP) profile, in particular of a reduced BP dipping at night, and the high prevalence of specific hy...